Factor VII (Proconvertin) (Last Updated - 3/29/2005)
-gets activated to form Factor VIIa (the initial step of the extrinsic pathway) --> efficacy of this reaction is increased by tissue factor
-1/2-Life:
~6 hrs.
-click here to view an image of the clotting cascade
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References:
Goodman & Gilman's: The Pharmacologic Basis Of Therapeutics - 10th Edition - 2001. Chapter 55.